产品资料

Trk A (phospho Tyr791) Antibody

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产品名称: Trk A (phospho Tyr791) Antibody
产品型号:
产品展商: immunoclone
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简单介绍

Trk A (phospho Tyr791) Antibody迅速增长的产品线包括一抗、二抗、**测定及细胞检测试剂盒、蛋白/多肽、激动剂/拮抗剂/活化剂/抑制剂及裂解物等。Trk A (phospho Tyr791) Antibody严格的质量控制和验证实验包括各种不同的应用：WB、细胞**荧光、**组化、流式细胞术、ELISA、CHIP、IP和peptide array。


Trk A (phospho Tyr791) Antibody  的详细介绍

Trk A (phospho Tyr791) AntibodyProduct Profile

Product Name Trk A (phospho Tyr791) Antibody
Antibody Type Primary Antibodies
Product description 
					

						Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway.1) Tina Garofalo, J. Biol. Chem., Dec 1998; 273: 35153.
					

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Immunogen 
Trk A (phospho Tyr791) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 791 (P-V-Y (p)-L-D) derived from Human Trk A.

Trk A (phospho Tyr791) AntibodyKey Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC

Species Reactivity

Human

Concentration 1mg/ml
Purification Affinity purified

Trk A (phospho Tyr791) AntibodyTarget Information

Gene Symbol NTRK1
Alternative Names
TRKA
TRK
NTRK1
p140-TrkA
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Molecular Weight(MW) 140 kDa
Tissue Specificity The antibody detects endogenous levels of Trk A only when phosphorylated at tyrosine 791.

Trk A (phospho Tyr791) AntibodyDatabase Links

Entrez Gene 4914
Protein Accession NP_002520.2

Trk A (phospho Tyr791) AntibodyApplication

  • Application

    Immunohistochemical analysis of paraffin-embedded human brain tissue, using Trk A (phospho-Tyr791) antibody (left) or the same antibody preincubated with blocking peptide (right).

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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